- Spawns the last pill you used. Blue Baby, The Lost), * devil pool, devil room pool, devil deal, red, black, star, moon, When used, gives a random familiar for the entire floor. Binding of Isaac: Rebirth Wiki During this time he can walk over enemies to mark them for death. Like put it into my file search bar because I tried that and it didn't work. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, Replacing all 12 containers with broken hearts will kill you instantly. in The Chest as Apollyon, Upon entering a room with enemies, spawns a Black Locust that deals quadruple Isaac's damage, applied as two hits of double damage, UNLOCK: Unlock this trinket by defeating The Lamb as Apollyon, At the start of each new hostile room you spawn 2-5 white attack flies, which will target a nearby enemy and deal double your tear damage to it, UNLOCK: Unlock this trinket by defeating Boss Rush as Apollyon, When killing an enemy, you have a very small chance to gain the ability to fly for the rest of the room, UNLOCK: Unlock this trinket by defeating Greedier Mode with Azazel, Stem Cell heals Isaac's red heart containers to 50% each floor, If Isaac already has 50% health or more, it heals half of a heart instead, UNLOCK: Unlock this trinket by defeating Greedier Mode with Samson, Fully recharges your active item at the start of each boss fight, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Zaratus, Gives you the Holy Mantle shield effect at the start of every new floor, which protects you from the next hit of damage you take, Does not recharge until the start of the next floor, Stacks with the effects from Holy Mantle and Blanket, but it does not stack with Holy Card, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Ep and Mills, Using your active item while holding this trinket will drop it back on a pedestal on the ground, Also after taking damage, you have a very small chance to drop one of your passive items, One-time use active items will be consumed and not dropped, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by MarkusLeben and iguesti, *, yellow, golden, box, block, square, cube, Holding this trinket will cause the Angel mini bosses to drop normal items instead of Key Pieces, Added as part of the Afterbirth+ Booster Pack #2, designed by Edmund McMillen, While held, the last door Isaac went through stays open, allowing him to leave the room even if enemies are in it, This trinket works on boss rooms (except Ultra Greed) and devil rooms containing Krampus, allowing you to exit out mid-fight, UNLOCK: Unlock this trinket by blowing up doors and secret room walls 50 times, *, door, stop, wedge, cheese, wood, brown, hodor, game of thrones, Wylis, After being picked up, a yellow laser chain now flows through Isaac's familiars, Added as part of the Afterbirth+ Booster Pack #4 and based on the Steam Workshop mod created by Strawrat and Aczom, While held, spawns +1 friendly blue fly every time you pick up a coin, Added as part of the Afterbirth+ Booster Pack #5. Changed to 2 room recharge, * golden chest pool, gold chest pool, item room, treasure room, item room pool, bob sloth, ?, Satan and The Lamb as Tainted Lost. It rerolls enemies and pickups it comes into contact with, then despawns. white, square, When used, you have a chance of getting one of the three following effects: Treasure Map (floor layout), Compass (map icons) or Blue Map (secret room locations), REPENTANCE - Book of Secrets now avoids giving mapping effects that the player already has. When used, fills the entire room with poop! Be warned though, Mom's leg can also stomp and hurt Isaac too! UNLOCK: Unlock this item by defeating Ultra Greed as Apollyon, At the start of each new hostile room, you have a 20% chance to gain a random charmed familiar which will fight for you, The charmed enemy has its own health bar and will die if it takes enough damage, Charmed enemies persist between each room and floor for as long as they stay alive, Allows you to have more than one charmed familiar at a time if you can keep them alive, * pokemon, phone, black, green, blue, gps, Every time one of your tears hits an enemy, it has a chance to start bleeding, which will cause it to take damage every 5 seconds, The bleed damage dealt by BackStabber is based on how quickly an enemy is moving (faster enemies take more damage), Damaging enemies from behind gives the bleed effect a 100% chance to apply, While an enemy bleeds, they leave behind creep that damages other enemies, The tear that inflicts the bleed effect also deals double damage, *, knife, dagger, red, heart, silver, knife, When used, Sharp Straw will deal damage to all enemies in the room, The damage dealt is equal to Isaac's current tear damage plus 10% of the enemy's max health, Every time this item deals damage, it has a 15% chance to drop 1/2 red hearts, REPENTANCE - Sharp Straw is now only able to generate half red hearts (previously, it generated half soul hearts if the player had no heart containers), A razor blade orbital that deals contact damage and applies the bleeding status effect to enemies and bosses, which will cause them to take damage every 5 seconds, The contact damage dealt by Mom's Razor is based on how quickly an enemy is moving (faster enemies take more damage), Its speed is not affected by the Guardian Angel item, An eye orbital that shoots tears that deal 3.5 damage and deals 2 contact damage per tick to enemies, The damage dealt by this orbital does not scale with damage upgrades, REPENTANCE - Bloodshot Eye now blocks enemy shots, has increased shot speed and rate of fire, and now only shoots when lined up with enemies, When used, spawns a charmed random white delirium version of a boss, that will fight for you and kill other enemies for the rest of the current room, Possible bosses spawned include most bosses in the game, Some bosses' effects can harm Isaac. Click here to jump to that post. the lost item pool, A familiar that follows Isaac and fires black tar tears, which slow enemy movement and projectile speed for a few seconds, Little Gish fires tears at a rate of 1 tear per second, A Guaranteed drop from the Gish boss fight, UNLOCK: Unlock this item by beating the Depths 20 times and killing the Gish boss, * item room, treasure room, item room pool, grey, gray, yellow, eyes, face, A familiar that follows Isaac and fires homing tears that deal 3.5 damage each, Has a high chance to drop from the Steven boss fight, Little Steven fires tears at a rate of 1 tear per second with a slightly longer range than other familiars, UNLOCK: Unlock this item by killing the Steven boss for the first time, * boss room pool, boss room item, item room, treasure room, item room pool, black, baby, white, eyes, UNLOCK: Unlock this item by killing Mom (Mom's Foot or Mom's Heart) using The Bible, * angel room pool, god room pool, angel room item, boss room pool, boss room item, item room, *, brown, red, tup, carton, box, golden chest pool, gold chest pool, Item Pool: Boss Room, Gold/Stone Chest, Mom's Chest, *, white, necklace, grey, gray, moms pearls, mom pearls, The Car Battery causes your spacebar item to activate twice on each use, For example, with Yum Heart you would heal 2 full red hearts instead of 1, Upon use, gives you a duplicate of each familiar you have for the current room, It will not 'double' your familiars as the tagline suggests - if you have 2 of one kind, it will only give you an extra one, If the familiar only appears when taking damage (i.e. Move to another floor on the same seed. Unlocked from Challenge #24 - PAY TO PLAY, Power Pill - Gives you invulnerability and the ability to damage enemies for a short while (similar to The Gamekid effect), Re-Lax - Causes Isaac to spawn poops behind him while he walks for a few seconds. Blood Bag) it will be rerolled into a random Item Room item, Cannot remove Azazel's Brimstone laser, or The Lost's Holy Mantle, REPENTANCE - Full run reroll effects are now able to remove heart containers and transformations if losing the respective items during the reroll, UNLOCK: Unlock this item by blowing up 30 slot machines, * item room, treasure room, item room pool, dice pip, starting, pyramid, green, triange, When used, 'devolves' all enemies in the room which are currently alive into another weaker type of enemy, * item room, treasure room, item room pool, DIO, dice pip, orange, brown, turban, When used, copies the effect of the card you are currently holding without consuming it, The charge time of this item depends on the quality of the card you're holding, Using this with the ? For trinkets numbers, use "t15" Notice how it can autocomplete if you don't type the full name. ?, Satan and The Lamb as Tainted Magdalene, The first time you pick this trinket up, the heart container will be filled. chalice, indiana jones, * angel room pool, god room pool, angel room item, bird, white, Every time you use this item it deals 40 damage to all enemies in the room and Isaac also takes damage, The first use per room takes 1 full heart, then 0.5 hearts per use after that, Shields and invincibility effects do not prevent damage when using this item, Using with Isaac's Heart previously prevented you from taking damage, however in Repentance this was fixed, Using this item as The Lost will instantly kill him, even if you have Holy Mantle active, UNLOCK: Unlock this item by beating Satan with Samson, * item room, treasure room, item room pool, razor, straight, edge, barber, bloody, brown, silver, Follows behind Isaac and can be swung back and forth, dealing 5 contact damage per tick to anything it hits, Every time the hairball kills an enemy, it grows in size allowing it to deal more damage, This is one of the items which allows you to transform into Guppy, Moving to a new floor decreases the size of the hairball, * devil pool, devil room pool, devil deal, grey, brown, pile, guppys hairball, guppy hairball, A familiar that mirrors the player's movements and shoots tears directly at Isaac, Abel's tears do 3.5 damage, unless playing as Cain in which case they do 5, REPENTANCE - Abel now has an increased rate of fire, and will mirror to the other side of the room, even if it's off screen. purple, pink, circle, guppys collar, All of Isaac's tears now have a shield, allowing them to block an enemy projectile, If a tear blocks something, both Isaac's and the enemies tears are destroyed, * secret room pool, item room, treasure room, item room pool, white, lump, oval, When Isaac takes damage, he will start to leave a trail of blood creep behind him as he walks for the current room. or The Lamb, it will die instantly, Can also be thrown against a door to open it (Doesn't work against Mega Satan's door). Using Sumptorium as her will then cause all Clots to be consumed and return your hearts back to you. If used in a room with no enemies, Dark Esau will instantly spawn, Will chain up to two targets if you have Car Battery, if only one valid target is present it will be chained for twice the duration, UNLOCK: Unlock this item by defeating Delirium as Tainted Jacob, Rerolls all pedestal items, lowering all their internal item IDs by 1, For example: Brimstone's ID = 118, so it would be rerolled into Dead Bird (ID = 117), Sad Onion (ID = 1) will reroll into nothing, There are some gaps in item IDs which are skipped if no item exists, or will reroll into unexpected items if hidden items are present at that ID. Releasing Dark Esau will cause him to charge directly at Jacob and deal damage to anything in his path. Also, try the clipboard! ), Keeps the chance at 100% even after entering and leaving the angel room, meaning the door will not close after visiting, Makes it impossible to find Devil Rooms again, unless you find a way to remove or reroll this item away, or find the Duality item, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Maggy, A sack familiar that drops a sack every 5 or 6 rooms cleared (alternates between 5 and 6), UNLOCK: Unlock this item by defeating Greedier Mode as Cain, * back in black, ac/dc, bag, brown, pouch, pocket, bulge, Gives you an extra heart container for every 25 coins you are currently holding, up to a maximum of 4 extra HP at 99 coins held, If your coin counter goes below the required amount for a heart container, you will lose it again, This item works for the Keeper, allowing him to exceed his usual 2 health containers, However, if Keeper drops to under 2 health coins as a result of Greed's Gullet, he is unable to use a HP Up to increase his health back to 2, and has to regain the lost coins to do so, UNLOCK: Unlock this item by beating Challenge #35 (Pong), *, dollar, cash, sack, bag, pouch, greeds gullet, greed gullet, Gives you a random chance while firing tears to also fire a creep shot, which deals double your tear damage and places white creep on the floor infront of you that slows enemies down if they walk through it, Unlike some similar tear effects, your luck stat does not alter the chance for this effect to activate, A creep shot is also fired in a random direction after taking damage, While firing tears you have a 5% chance to fire a void tear.
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